Propofol infusion for ICU sedation in children

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Prolonged sedation with propofol in ICU patients: recovery and blood concentration changes during periodic interruptions in infusion.

Propofol (mean dose 2.85 mg kg-1 h-1) was administered for 4 days by continuous i.v. infusion for sedation in 14 agitated and restless ICU patients. This provided rapid control of the level of sedation. When the infusion was discontinued, adequate recovery with response to commands was obtained in most patients by 10 min. Recovery times and the decrease in blood propofol concentration were simi...

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Comparison between the effects of propofol-ketamine and propofol-fentanyl for sedation in cataract surgery

Background and Aim: Considering the importance of proper sedation in cataract surgery, this study was conducted to make a comparison between the effects of ketamine-propofol combination and fentanyl-propofol combination for sedation in phacoemulsification surgery. Methods: In this clinical trial study, 84 patients who were candidates for phacoemulsification cataract surgery were assigned to two...

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Propofol versus Midazolam for Sedation during Esophagogastroduodenoscopy in Children

BACKGROUND/AIMS To evaluate the efficacy and safety of propofol and midazolam for sedation during esophagogastroduodenoscopy (EGD) in children. METHODS We retrospectively reviewed the hospital records of 62 children who underwent ambulatory diagnostic EGD during 1-year period. Data were collected from 34 consecutive patients receiving propofol alone. Twenty-eight consecutive patients who rece...

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Dexmedetomidine sedation in ICU

Dexmedetomidine (DEX), a highly selective α(2)-adrenergic receptor agonist, is the newest agent introduced for sedation in intensive care unit (ICU). The sedation strategy for critically ill patients has stressed light sedation with daily awakening and assessment for neurologic, cognitive, and respiratory functions, since Society of Critical Care Medicine (SCCM) guidelines were presented in 200...

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Propofol infusion for sedation in the intensive care unit: preliminary report.

Propofol (2,6,di-isopropylphenol) was given by continuous intravenous infusion to provide sedation after cardiac surgery in 30 patients and its effects compared with those of midazolam given to a further 30 patients. Propofol infusion allowed rapid and accurate control of the level of sedation, which was satisfactory for longer than with midazolam. Patients given propofol recovered significantl...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 2002

ISSN: 0003-2409

DOI: 10.1046/j.1365-2044.2002.262633.x